CONTRIBUTOR(S): Vetstream Ltd, Fear Free,
Medication: Erythropoietin
Medication: Erythropoietin
Your dog has been prescribed erythropoietin for the treatment of anemia.
Key points:
• A synthetic form of human erythropoietin (a hormone produced by the kidneys that stimulates red blood cell production).
• Given by injection.
• Must be stored in a refrigerator and not allowed to freeze.
This information sheet is designed to help answer commonly asked questions and help you give the medication safely and effectively to your pet. It does not contain all available information for this medication. If you have other questions or need more information, contact your veterinarian or pharmacist. Always follow the dosing instructions provided by your veterinarian.
Name, Brand names, Class of medication and Storage
Name
- Erythropoietin (eh-ree-throw-poy-ee-tin).
Class of medication
- Synthetic human erythropoietin.
Storage
- Store in a refrigerator between 2-8°C (35.6-46.4°F). Do not freeze.
Why has my dog been prescribed erythropoietin?
Your veterinarian has prescribed erythropoietin to treat anemia caused by chronic kidney disease which has resulted in a fall in natural erythropoietin production. Erythropoietin stimulates the bone marrow to increase the production of red blood cells.
How is the medication given?
Erythropoietin is administered by injection.
Are there any side-effects or drug interactions?
Erythropoietin can have potential side-effects in dogs. As this is an unlicensed product, the information available is limited, but reported side-effects in dogs include; high blood pressure, seizures, pain, swelling, or redness at the site of the injection and allergic reaction.
It is important to monitor your dog closely for any signs of side-effects after receiving erythropoietin, and to contact your veterinarian immediately if you notice any concerning symptoms. Your veterinarian will recommend regular blood tests to monitor your dog’s response to the medication and to detect any potential side-effects early on.
Erythropoietin should not be administered to patients with high blood pressure.
Some patients will develop antibodies to this drug which will mean it no longer works to increase red cell production. This occurs in 20% of dogs after 4 or more weeks of treatment. This can result in a complete shut down of red cell production (pure red cell aplasia).
How long will my dog need to receive this medication?
This will be determined by the response your pet has to the drug. The frequency and length of treatment will depend on the patient’s response. As red cell production increases the frequency of administration will be reduced. Your veterinarian will advise you how long your dog will need this treatment.
How should I dispose of this medication if I don’t use it all?
All unused erythropoietin should be returned to your veterinary practice for disposal and must not be placed in household waste.
What if I miss a dose or give an extra dose?
If you miss a dose, give the dose as soon as possible but do not give a double dose.
My dog is unwell, should I still give the drug?
If your pet is unwell, contact your veterinarian for advice.
What should I do if this medication is accidentally given to another pet or taken by a human?
Erythropoietin should only be given to the dog that it has been prescribed for. If accidentally given to other pets, contact your veterinarian for advice.
If accidentally injected into a human, speak to your primary care physician or poison control center.
Will my dog need to be monitored while on erythropoietin?
Your veterinarian will regularly monitor your dog and perform blood tests while on erythropoietin.
Further information
If you have any concerns, further information on erythropoietin can be found on the package insert.
Europe & UK
- There are no veterinary drugs containing erythropoietin licensed for use in dogs in the UK. Your veterinary surgeon may prescribe a human drug containing erythropoietin and will be able to explain the use of off-license medications to you.
US
- There are no veterinary drugs containing erythropoietin licensed for use in dogs in the US. Your veterinarian may prescribe a human drug containing erythropoietin and will be able to explain the use of off-license medications to you.
Always follow the recommended dosage and contact your veterinary team or pharmacist if you have any questions regarding your dog’s medication.